The Case for Reactive Mass Oral Cholera Vaccinations
Identifieur interne : 006025 ( Main/Exploration ); précédent : 006024; suivant : 006026The Case for Reactive Mass Oral Cholera Vaccinations
Auteurs : Rita Reyburn [Corée du Sud] ; Jacqueline L. Deen [Corée du Sud] ; Rebecca F. Grais [France] ; Sujit K. Bhattacharya [Inde] ; Dipika Sur [Inde] ; Anna L. Lopez [Corée du Sud] ; Mohamed S. Jiddawi [Tanzanie] ; John D. Clemens [Corée du Sud] ; Lorenz Von Seidlein [Australie]Source :
- PLoS Neglected Tropical Diseases [ 1935-2727 ] ; 2011.
Abstract
The outbreak of cholera in Zimbabwe intensified interest in the control and prevention of cholera. While there is agreement that safe water, sanitation, and personal hygiene are ideal for the long term control of cholera, there is controversy about the role of newer approaches such as oral cholera vaccines (OCVs). In October 2009 the Strategic Advisory Group of Experts advised the World Health Organization to consider reactive vaccination campaigns in response to large cholera outbreaks. To evaluate the potential benefit of this pivotal change in WHO policy, we used existing data from cholera outbreaks to simulate the number of cholera cases preventable by reactive mass vaccination.
Datasets of cholera outbreaks from three sites with varying cholera endemicity—Zimbabwe, Kolkata (India), and Zanzibar (Tanzania)—were analysed to estimate the number of cholera cases preventable under differing response times, vaccine coverage, and vaccine doses.
The large cholera outbreak in Zimbabwe started in mid August 2008 and by July 2009, 98,591 cholera cases had been reported with 4,288 deaths attributed to cholera. If a rapid response had taken place and half of the population had been vaccinated once the first 400 cases had occurred, as many as 34,900 (40%) cholera cases and 1,695 deaths (40%) could have been prevented. In the sites with endemic cholera, Kolkata and Zanzibar, a significant number of cases could have been prevented but the impact would have been less dramatic. A brisk response is required for outbreaks with the majority of cases occurring during the early weeks. Even a delayed response can save a substantial number of cases and deaths in long, drawn-out outbreaks. If circumstances prevent a rapid response there are good reasons to roll out cholera mass vaccination campaigns well into the outbreak. Once a substantial proportion of a population is vaccinated, outbreaks in subsequent years may be reduced if not prevented. A single dose vaccine would be of advantage in short, small outbreaks.
We show that reactive vaccine use can prevent cholera cases and is a rational response to cholera outbreaks in endemic and non-endemic settings. In large and long outbreaks a reactive vaccination with a two-dose vaccine can prevent a substantial proportion of cases. To make mass vaccination campaigns successful, it would be essential to agree when to implement reactive vaccination campaigns and to have a dynamic and determined response team that is familiar with the logistic challenges on standby. Most importantly, the decision makers in donor and recipient countries have to be convinced of the benefit of reactive cholera vaccinations.
Url:
DOI: 10.1371/journal.pntd.0000952
PubMed: 21283614
PubMed Central: 3026767
Affiliations:
- Australie, Corée du Sud, France, Inde, Tanzanie
- Région capitale de Séoul, Île-de-France
- Paris, Séoul
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 002927
- to stream Pmc, to step Curation: 002777
- to stream Pmc, to step Checkpoint: 002154
- to stream Ncbi, to step Merge: 000973
- to stream Ncbi, to step Curation: 000973
- to stream Ncbi, to step Checkpoint: 000973
- to stream Main, to step Merge: 006357
- to stream Main, to step Curation: 006025
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The Case for Reactive Mass Oral Cholera Vaccinations</title>
<author><name sortKey="Reyburn, Rita" sort="Reyburn, Rita" uniqKey="Reyburn R" first="Rita" last="Reyburn">Rita Reyburn</name>
<affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>International Vaccine Institute (IVI), Seoul, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>International Vaccine Institute (IVI), Seoul</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Deen, Jacqueline L" sort="Deen, Jacqueline L" uniqKey="Deen J" first="Jacqueline L." last="Deen">Jacqueline L. Deen</name>
<affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>International Vaccine Institute (IVI), Seoul, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>International Vaccine Institute (IVI), Seoul</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Grais, Rebecca F" sort="Grais, Rebecca F" uniqKey="Grais R" first="Rebecca F." last="Grais">Rebecca F. Grais</name>
<affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Epicentre, Paris, France</addr-line>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Epicentre, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bhattacharya, Sujit K" sort="Bhattacharya, Sujit K" uniqKey="Bhattacharya S" first="Sujit K." last="Bhattacharya">Sujit K. Bhattacharya</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>NICED, Kolkata, India</addr-line>
</nlm:aff>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>NICED, Kolkata</wicri:regionArea>
<wicri:noRegion>Kolkata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sur, Dipika" sort="Sur, Dipika" uniqKey="Sur D" first="Dipika" last="Sur">Dipika Sur</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>NICED, Kolkata, India</addr-line>
</nlm:aff>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>NICED, Kolkata</wicri:regionArea>
<wicri:noRegion>Kolkata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lopez, Anna L" sort="Lopez, Anna L" uniqKey="Lopez A" first="Anna L." last="Lopez">Anna L. Lopez</name>
<affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>International Vaccine Institute (IVI), Seoul, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>International Vaccine Institute (IVI), Seoul</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jiddawi, Mohamed S" sort="Jiddawi, Mohamed S" uniqKey="Jiddawi M" first="Mohamed S." last="Jiddawi">Mohamed S. Jiddawi</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Ministry of Health and Social Welfare, Zanzibar, Tanzania</addr-line>
</nlm:aff>
<country xml:lang="fr">Tanzanie</country>
<wicri:regionArea>Ministry of Health and Social Welfare, Zanzibar</wicri:regionArea>
<wicri:noRegion>Zanzibar</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Clemens, John D" sort="Clemens, John D" uniqKey="Clemens J" first="John D." last="Clemens">John D. Clemens</name>
<affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>International Vaccine Institute (IVI), Seoul, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>International Vaccine Institute (IVI), Seoul</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Von Seidlein, Lorenz" sort="Von Seidlein, Lorenz" uniqKey="Von Seidlein L" first="Lorenz" last="Von Seidlein">Lorenz Von Seidlein</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><addr-line>Menzies School of Health Research, Casuarina, Australia</addr-line>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Menzies School of Health Research, Casuarina</wicri:regionArea>
<wicri:noRegion>Casuarina</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">21283614</idno>
<idno type="pmc">3026767</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3026767</idno>
<idno type="RBID">PMC:3026767</idno>
<idno type="doi">10.1371/journal.pntd.0000952</idno>
<date when="2011">2011</date>
<idno type="wicri:Area/Pmc/Corpus">002927</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">002927</idno>
<idno type="wicri:Area/Pmc/Curation">002777</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">002777</idno>
<idno type="wicri:Area/Pmc/Checkpoint">002154</idno>
<idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002154</idno>
<idno type="wicri:Area/Ncbi/Merge">000973</idno>
<idno type="wicri:Area/Ncbi/Curation">000973</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000973</idno>
<idno type="wicri:doubleKey">1935-2727:2011:Reyburn R:the:case:for</idno>
<idno type="wicri:Area/Main/Merge">006357</idno>
<idno type="wicri:Area/Main/Curation">006025</idno>
<idno type="wicri:Area/Main/Exploration">006025</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The Case for Reactive Mass Oral Cholera Vaccinations</title>
<author><name sortKey="Reyburn, Rita" sort="Reyburn, Rita" uniqKey="Reyburn R" first="Rita" last="Reyburn">Rita Reyburn</name>
<affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>International Vaccine Institute (IVI), Seoul, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>International Vaccine Institute (IVI), Seoul</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Deen, Jacqueline L" sort="Deen, Jacqueline L" uniqKey="Deen J" first="Jacqueline L." last="Deen">Jacqueline L. Deen</name>
<affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>International Vaccine Institute (IVI), Seoul, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>International Vaccine Institute (IVI), Seoul</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Grais, Rebecca F" sort="Grais, Rebecca F" uniqKey="Grais R" first="Rebecca F." last="Grais">Rebecca F. Grais</name>
<affiliation wicri:level="3"><nlm:aff id="aff2"><addr-line>Epicentre, Paris, France</addr-line>
</nlm:aff>
<country xml:lang="fr">France</country>
<wicri:regionArea>Epicentre, Paris</wicri:regionArea>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bhattacharya, Sujit K" sort="Bhattacharya, Sujit K" uniqKey="Bhattacharya S" first="Sujit K." last="Bhattacharya">Sujit K. Bhattacharya</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>NICED, Kolkata, India</addr-line>
</nlm:aff>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>NICED, Kolkata</wicri:regionArea>
<wicri:noRegion>Kolkata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sur, Dipika" sort="Sur, Dipika" uniqKey="Sur D" first="Dipika" last="Sur">Dipika Sur</name>
<affiliation wicri:level="1"><nlm:aff id="aff3"><addr-line>NICED, Kolkata, India</addr-line>
</nlm:aff>
<country xml:lang="fr">Inde</country>
<wicri:regionArea>NICED, Kolkata</wicri:regionArea>
<wicri:noRegion>Kolkata</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Lopez, Anna L" sort="Lopez, Anna L" uniqKey="Lopez A" first="Anna L." last="Lopez">Anna L. Lopez</name>
<affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>International Vaccine Institute (IVI), Seoul, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>International Vaccine Institute (IVI), Seoul</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Jiddawi, Mohamed S" sort="Jiddawi, Mohamed S" uniqKey="Jiddawi M" first="Mohamed S." last="Jiddawi">Mohamed S. Jiddawi</name>
<affiliation wicri:level="1"><nlm:aff id="aff4"><addr-line>Ministry of Health and Social Welfare, Zanzibar, Tanzania</addr-line>
</nlm:aff>
<country xml:lang="fr">Tanzanie</country>
<wicri:regionArea>Ministry of Health and Social Welfare, Zanzibar</wicri:regionArea>
<wicri:noRegion>Zanzibar</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Clemens, John D" sort="Clemens, John D" uniqKey="Clemens J" first="John D." last="Clemens">John D. Clemens</name>
<affiliation wicri:level="3"><nlm:aff id="aff1"><addr-line>International Vaccine Institute (IVI), Seoul, Korea</addr-line>
</nlm:aff>
<country xml:lang="fr">Corée du Sud</country>
<wicri:regionArea>International Vaccine Institute (IVI), Seoul</wicri:regionArea>
<placeName><settlement type="city">Séoul</settlement>
<region type="capital">Région capitale de Séoul</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Von Seidlein, Lorenz" sort="Von Seidlein, Lorenz" uniqKey="Von Seidlein L" first="Lorenz" last="Von Seidlein">Lorenz Von Seidlein</name>
<affiliation wicri:level="1"><nlm:aff id="aff5"><addr-line>Menzies School of Health Research, Casuarina, Australia</addr-line>
</nlm:aff>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Menzies School of Health Research, Casuarina</wicri:regionArea>
<wicri:noRegion>Casuarina</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j">PLoS Neglected Tropical Diseases</title>
<idno type="ISSN">1935-2727</idno>
<idno type="eISSN">1935-2735</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><sec><title>Introduction</title>
<p>The outbreak of cholera in Zimbabwe intensified interest in the control and prevention of cholera. While there is agreement that safe water, sanitation, and personal hygiene are ideal for the long term control of cholera, there is controversy about the role of newer approaches such as oral cholera vaccines (OCVs). In October 2009 the Strategic Advisory Group of Experts advised the World Health Organization to consider reactive vaccination campaigns in response to large cholera outbreaks. To evaluate the potential benefit of this pivotal change in WHO policy, we used existing data from cholera outbreaks to simulate the number of cholera cases preventable by reactive mass vaccination.</p>
</sec>
<sec><title>Methods</title>
<p>Datasets of cholera outbreaks from three sites with varying cholera endemicity—Zimbabwe, Kolkata (India), and Zanzibar (Tanzania)—were analysed to estimate the number of cholera cases preventable under differing response times, vaccine coverage, and vaccine doses.</p>
</sec>
<sec><title>Findings</title>
<p>The large cholera outbreak in Zimbabwe started in mid August 2008 and by July 2009, 98,591 cholera cases had been reported with 4,288 deaths attributed to cholera. If a rapid response had taken place and half of the population had been vaccinated once the first 400 cases had occurred, as many as 34,900 (40%) cholera cases and 1,695 deaths (40%) could have been prevented. In the sites with endemic cholera, Kolkata and Zanzibar, a significant number of cases could have been prevented but the impact would have been less dramatic. A brisk response is required for outbreaks with the majority of cases occurring during the early weeks. Even a delayed response can save a substantial number of cases and deaths in long, drawn-out outbreaks. If circumstances prevent a rapid response there are good reasons to roll out cholera mass vaccination campaigns well into the outbreak. Once a substantial proportion of a population is vaccinated, outbreaks in subsequent years may be reduced if not prevented. A single dose vaccine would be of advantage in short, small outbreaks.</p>
</sec>
<sec><title>Conclusions</title>
<p>We show that reactive vaccine use can prevent cholera cases and is a rational response to cholera outbreaks in endemic and non-endemic settings. In large and long outbreaks a reactive vaccination with a two-dose vaccine can prevent a substantial proportion of cases. To make mass vaccination campaigns successful, it would be essential to agree when to implement reactive vaccination campaigns and to have a dynamic and determined response team that is familiar with the logistic challenges on standby. Most importantly, the decision makers in donor and recipient countries have to be convinced of the benefit of reactive cholera vaccinations.</p>
</sec>
</div>
</front>
<back><div1 type="bibliography"><listBibl><biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Bhattacharya, S" uniqKey="Bhattacharya S">S Bhattacharya</name>
</author>
<author><name sortKey="Black, R" uniqKey="Black R">R Black</name>
</author>
<author><name sortKey="Bourgeois, L" uniqKey="Bourgeois L">L Bourgeois</name>
</author>
<author><name sortKey="Clemens, J" uniqKey="Clemens J">J Clemens</name>
</author>
<author><name sortKey="Cravioto, A" uniqKey="Cravioto A">A Cravioto</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Clemens, Jd" uniqKey="Clemens J">JD Clemens</name>
</author>
<author><name sortKey="Sack, Da" uniqKey="Sack D">DA Sack</name>
</author>
<author><name sortKey="Harris, Jr" uniqKey="Harris J">JR Harris</name>
</author>
<author><name sortKey="Chakraborty, J" uniqKey="Chakraborty J">J Chakraborty</name>
</author>
<author><name sortKey="Khan, Mr" uniqKey="Khan M">MR Khan</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Clemens, Jd" uniqKey="Clemens J">JD Clemens</name>
</author>
<author><name sortKey="Sack, Da" uniqKey="Sack D">DA Sack</name>
</author>
<author><name sortKey="Harris, Jr" uniqKey="Harris J">JR Harris</name>
</author>
<author><name sortKey="Van Loon, F" uniqKey="Van Loon F">F Van Loon</name>
</author>
<author><name sortKey="Chakraborty, J" uniqKey="Chakraborty J">J Chakraborty</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Lucas, Me" uniqKey="Lucas M">ME Lucas</name>
</author>
<author><name sortKey="Deen, Jl" uniqKey="Deen J">JL Deen</name>
</author>
<author><name sortKey="Von Seidlein, L" uniqKey="Von Seidlein L">L von Seidlein</name>
</author>
<author><name sortKey="Wang, Xy" uniqKey="Wang X">XY Wang</name>
</author>
<author><name sortKey="Ampuero, J" uniqKey="Ampuero J">J Ampuero</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Girard, Mp" uniqKey="Girard M">MP Girard</name>
</author>
<author><name sortKey="Steele, D" uniqKey="Steele D">D Steele</name>
</author>
<author><name sortKey="Chaignat, Cl" uniqKey="Chaignat C">CL Chaignat</name>
</author>
<author><name sortKey="Kieny, Mp" uniqKey="Kieny M">MP Kieny</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sridhar, S" uniqKey="Sridhar S">S Sridhar</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sur, D" uniqKey="Sur D">D Sur</name>
</author>
<author><name sortKey="Lopez, Al" uniqKey="Lopez A">AL Lopez</name>
</author>
<author><name sortKey="Kanungo, S" uniqKey="Kanungo S">S Kanungo</name>
</author>
<author><name sortKey="Paisley, A" uniqKey="Paisley A">A Paisley</name>
</author>
<author><name sortKey="Manna, B" uniqKey="Manna B">B Manna</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sur, D" uniqKey="Sur D">D Sur</name>
</author>
<author><name sortKey="Lopez, Al" uniqKey="Lopez A">AL Lopez</name>
</author>
<author><name sortKey="Kanungo, S" uniqKey="Kanungo S">S Kanungo</name>
</author>
<author><name sortKey="Paisley, A" uniqKey="Paisley A">A Paisley</name>
</author>
<author><name sortKey="Manna, B" uniqKey="Manna B">B Manna</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Sur, D" uniqKey="Sur D">D Sur</name>
</author>
<author><name sortKey="Deen, Jl" uniqKey="Deen J">JL Deen</name>
</author>
<author><name sortKey="Manna, B" uniqKey="Manna B">B Manna</name>
</author>
<author><name sortKey="Niyogi, Sk" uniqKey="Niyogi S">SK Niyogi</name>
</author>
<author><name sortKey="Deb, Ak" uniqKey="Deb A">AK Deb</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Jertborn, M" uniqKey="Jertborn M">M Jertborn</name>
</author>
<author><name sortKey="Svennerholm, Am" uniqKey="Svennerholm A">AM Svennerholm</name>
</author>
<author><name sortKey="Holmgren, J" uniqKey="Holmgren J">J Holmgren</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Naficy, A" uniqKey="Naficy A">A Naficy</name>
</author>
<author><name sortKey="Rao, Mr" uniqKey="Rao M">MR Rao</name>
</author>
<author><name sortKey="Paquet, C" uniqKey="Paquet C">C Paquet</name>
</author>
<author><name sortKey="Antona, D" uniqKey="Antona D">D Antona</name>
</author>
<author><name sortKey="Sorkin, A" uniqKey="Sorkin A">A Sorkin</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Laforce, Fm" uniqKey="Laforce F">FM LaForce</name>
</author>
<author><name sortKey="Konde, K" uniqKey="Konde K">K Konde</name>
</author>
<author><name sortKey="Viviani, S" uniqKey="Viviani S">S Viviani</name>
</author>
<author><name sortKey="Preziosi, Mp" uniqKey="Preziosi M">MP Preziosi</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
<biblStruct><analytic><author><name sortKey="Ali, M" uniqKey="Ali M">M Ali</name>
</author>
<author><name sortKey="Emch, M" uniqKey="Emch M">M Emch</name>
</author>
<author><name sortKey="Von Seidlein, L" uniqKey="Von Seidlein L">L von Seidlein</name>
</author>
<author><name sortKey="Yunus, M" uniqKey="Yunus M">M Yunus</name>
</author>
<author><name sortKey="Sack, Da" uniqKey="Sack D">DA Sack</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Longini, Im" uniqKey="Longini I">IM Longini</name>
</author>
<author><name sortKey="Nizam, A" uniqKey="Nizam A">A Nizam</name>
</author>
<author><name sortKey="Ali, M" uniqKey="Ali M">M Ali</name>
</author>
<author><name sortKey="Yunus, M" uniqKey="Yunus M">M Yunus</name>
</author>
<author><name sortKey="Shenvi, N" uniqKey="Shenvi N">N Shenvi</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Anh, Dd" uniqKey="Anh D">DD Anh</name>
</author>
<author><name sortKey="Canh Do, G" uniqKey="Canh Do G">G Canh do</name>
</author>
<author><name sortKey="Lopez, Al" uniqKey="Lopez A">AL Lopez</name>
</author>
<author><name sortKey="Thiem, Vd" uniqKey="Thiem V">VD Thiem</name>
</author>
<author><name sortKey="Long, Pt" uniqKey="Long P">PT Long</name>
</author>
</analytic>
</biblStruct>
<biblStruct><analytic><author><name sortKey="Mahalanabis, D" uniqKey="Mahalanabis D">D Mahalanabis</name>
</author>
<author><name sortKey="Lopez, Al" uniqKey="Lopez A">AL Lopez</name>
</author>
<author><name sortKey="Sur, D" uniqKey="Sur D">D Sur</name>
</author>
<author><name sortKey="Deen, J" uniqKey="Deen J">J Deen</name>
</author>
<author><name sortKey="Manna, B" uniqKey="Manna B">B Manna</name>
</author>
</analytic>
</biblStruct>
<biblStruct></biblStruct>
</listBibl>
</div1>
</back>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>Corée du Sud</li>
<li>France</li>
<li>Inde</li>
<li>Tanzanie</li>
</country>
<region><li>Région capitale de Séoul</li>
<li>Île-de-France</li>
</region>
<settlement><li>Paris</li>
<li>Séoul</li>
</settlement>
</list>
<tree><country name="Corée du Sud"><region name="Région capitale de Séoul"><name sortKey="Reyburn, Rita" sort="Reyburn, Rita" uniqKey="Reyburn R" first="Rita" last="Reyburn">Rita Reyburn</name>
</region>
<name sortKey="Clemens, John D" sort="Clemens, John D" uniqKey="Clemens J" first="John D." last="Clemens">John D. Clemens</name>
<name sortKey="Deen, Jacqueline L" sort="Deen, Jacqueline L" uniqKey="Deen J" first="Jacqueline L." last="Deen">Jacqueline L. Deen</name>
<name sortKey="Lopez, Anna L" sort="Lopez, Anna L" uniqKey="Lopez A" first="Anna L." last="Lopez">Anna L. Lopez</name>
</country>
<country name="France"><region name="Île-de-France"><name sortKey="Grais, Rebecca F" sort="Grais, Rebecca F" uniqKey="Grais R" first="Rebecca F." last="Grais">Rebecca F. Grais</name>
</region>
</country>
<country name="Inde"><noRegion><name sortKey="Bhattacharya, Sujit K" sort="Bhattacharya, Sujit K" uniqKey="Bhattacharya S" first="Sujit K." last="Bhattacharya">Sujit K. Bhattacharya</name>
</noRegion>
<name sortKey="Sur, Dipika" sort="Sur, Dipika" uniqKey="Sur D" first="Dipika" last="Sur">Dipika Sur</name>
</country>
<country name="Tanzanie"><noRegion><name sortKey="Jiddawi, Mohamed S" sort="Jiddawi, Mohamed S" uniqKey="Jiddawi M" first="Mohamed S." last="Jiddawi">Mohamed S. Jiddawi</name>
</noRegion>
</country>
<country name="Australie"><noRegion><name sortKey="Von Seidlein, Lorenz" sort="Von Seidlein, Lorenz" uniqKey="Von Seidlein L" first="Lorenz" last="Von Seidlein">Lorenz Von Seidlein</name>
</noRegion>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006025 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 006025 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Asie |area= AustralieFrV1 |flux= Main |étape= Exploration |type= RBID |clé= PMC:3026767 |texte= The Case for Reactive Mass Oral Cholera Vaccinations }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21283614" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \ | NlmPubMed2Wicri -a AustralieFrV1
This area was generated with Dilib version V0.6.33. |